People Behind The Science Podcast - Stories From Scientists About Science, Life, Research, And Science Careers

705: Engineering New Enzymes and Predicting the Biochemical Activity of Proteins - Dr. Mary Jo Ondrechen

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Sinopsis

Dr. Mary Jo Ondrechen is Professor of Chemistry and Chemical Biology at Northeastern University. In the lab, Mary Jo uses theory and computation to better understand how molecules work. In particular she works on enzymes which are proteins that catalyze chemical reactions. Mary Jo and her team also develop methods and theories to interpret genomic data, and they work on the computational side of drug discovery, helping medicinal chemists develop new drugs, treatments, and diagnostics. When she’s not at work, you can often find Mary Jo out running, tending to her vegetable garden, and cooking. She is also interested in herbs, spices, and medicinal plants. She earned her bachelor's degree in Chemistry from Reed College, and she was awarded her PhD in Chemistry and Chemical Physics from Northwestern University. Afterwards, Mary Jo completed a postdoctoral fellowship at the University of Chicago and subsequently a NATO Postdoctoral Fellowship at Tel-Aviv University in Israel. She joined the faculty at Northeaster