Nature Podcast

In this episode:00:45 Making a more diverse human genomeThe first draft of the human genome ushered in a new era of genetics research. Since its publication, researchers have constructed ever more accurate ‘reference genomes’ – baselines against which others are compared. But these are based on the DNA of a small number of people, and don’t represent the genetic variation known to exist across human populations. To address this, a consortium of researchers have published the first draft of a ‘pangenome’, which combines the genomes of 47 genetically diverse individuals. This draft provides a more complete picture of the human genome, and is the starting point for a project that aims to include sequences from 350 individuals.Research article: Liao et al. Research article: Vollger et al.Research article: Guarracino et al.News and Views Forum: Human pangenome supports analysis of complex genomic regions08:33 Research HighlightsA wearable sensor that lets users see infrared light, and how a vulture’s culture can i