Nature Podcast

Cancer's power harnessed — lymphoma mutations supercharge T cells

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Sinopsis

In this episode:0:46 Borrowing tricks from cancer could help improve immunotherapyT cell based immunotherapies have revolutionised the treatment of certain types of cancer. However these therapies — which involved taking someone’s own T cells and reprogramming them to kill cancer cells — have struggled to treat solid tumours, which put up multiple defences. To overcome these, a team has taken mutations found in cancer cells that help them thrive and put them into therapeutic T cells. Their results show these powered-up cells are more efficient at targeting solid tumours, but don’t turn cancerous themselves.Research article: Garcia et al.11:39 Research HighlightsHow researchers solved a submerged-sprinkler problem named after Richard Feynman, and what climate change is doing to high-altitude environmental records in Switzerland.Research Highlight: The mystery of Feynman’s sprinkler is solved at lastResearch Highlight: A glacier’s ‘memory’ is fading because of climate change14:28 What might the car batteries of