Nature Podcast

Human brain organoids implanted into rats could offer new way to model disease

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Sinopsis

In this episode:00:45 Implanted brain organoids could offer new insights into diseaseBrain organoids — lab-grown, self-organizing structures made of stem cells — are used in research to better understand brain development and disease progression. However, these structures lack connections seen in real brains, limiting their usefulness. To overcome this, a team has now transplanted human organoids into the brains of newborn rats, showing that these implanted organoids respond to stimuli and could influence the animals’ behaviour.Research article: Revah et al.News and Views: Human brain organoids influence rat behaviour09:20 Research HighlightsThe subtle timing shift that gives jazz music its ‘swing’, and why hydrogen power could be a cost-effective way to reduce heavy industry emissions in China. Research Highlight: What gives jazz its swing? A delay makes the differenceResearch Highlight: Hydrogen could help China’s heavy industry to get greener11:46 The exoskeleton boot that makes walking more efficientWeara