Heart Podcast

In this edition of the Heart Podcast, associate editor Dr James Rudd chats to Professor Adam Timmis from the Barts Heart Centre, London, UK about his recent publication "A 10-year prognostic model for patients with suspected angina attending a chest pain clinic" http://heart.bmj.com/content/early/2016/02/29/heartjnl-2015-308994.full?sid=bd5e1edf-49cd-4a7d-b2cc-17f0c311890d. They discuss the motivation for his study, debate diagnosis vs. prognosis in angina, and cover how the online prognosis calculator can be applied in the local chest pain clinic. Calculator: https://www.sealedenvelope.com/trials/pisa/

In this episode of the Heart Podcast, Heart associate editor Dr James Rudd is joined by Dr Kaspar Broch of the Oslo University Hospital, Norway to discuss his recent paper in Heart entitled: "Controlled release metoprolol for aortic regurgitation: A randomised clinical trial" They discuss the rationale for beta-blockers in aortic regurgitation and the results of this first clinical trial of these agents. Full paper >> heart.bmj.com/content/102/3/191.…-a075-27b877e18613

Heart digital media editor Dr. James Rudd is joined by Dr Michelle Ploutz from the Department of Pediatric Cardiology, Children’s National Health System, Washington, DC, to discuss her recent paper in Heart, entitled "Handheld echocardiographic screening for rheumatic heart disease by non-experts". They cover using echocardiography, performed by trained local nurses, to diagnose rheumatic heart disease in Uganda. The need for this approach, and how it fared in this study of 1000 African school children are revealed. Read the full article here: http://heart.bmj.com/content/102/1/35.full.

Dr Divaka Perera from King's College, London and Guy's and St Thomas' Hopsital joins Dr James Rudd, associate editor at Heart, to discuss his recent Education in Heart paper titled: "Ischaemic cardiomyopathy: pathophysiology, assessment and the role of revascularisation" They cover the aetiology of ischaemic cardiomyopathy, the definitions of stunning, hibernation and viability and what the trials and guidelines can tell us. Optimal imaging strategies are debated. There is also mention of the REVIVED BCIS-2 study, of which Dr Perera is PI.

In this episode of the Heart Podcast, Heart Digital Media Editor Dr James Rudd is in conversation with Dr Chris Fordyce from the Duke Clinical Research Institute. His team has just published an Education in Heart paper on "Optimal non-invasive imaging test selection for the diagnosis of ischemic heart disease." In this podcast, they discuss the similarities and differences between the international guidelines on the investigation of chest pain. They also highlight the results of the landmark PROMISE and SCOT-HEART studies and discuss how the results of these trials might influence future guidelines. The paper contains many high-resolution multimedia elements, along with MCQs to test your knowledge in this area.

In this podcast Dr James Rudd talks to Dr Sarah Clarke, President of the British Cardiovascular Society and Editor of the Education in Heart section of the journal. They talk about the education stream of the journal, new multimedia developments, and aligning content with the ESC curriculum.

In this podcast Dr James Rudd talks to Professor Stephen Nicholls, consultant cardiologist and Deputy Director of the South Australian Health and Medical Research Institute in Adelaide, at the 2015 European Cardiology meeting in London. They discuss the next generation of lipid therapies and imaging as a surrogate marker of disease.

In this podcast Dr James Rudd speaks to Dr Alexander Lyon, consultant cardiologist at the Royal Brompton Hospital, about the effects of cancer treatments on the heart, the problems of an aging population, and the new field of cardio-oncology. Editorial >> http://heart.bmj.com/content/early/2015/09/09/heartjnl-2015-308208.full Full paper >> http://heart.bmj.com/content/early/2015/09/08/heartjnl-2015-307848.full

Editor-in-Chief Dr Catherine Otto talks to Dr Elizabeth Mostofsky at the Cardiac Society of Australia & New Zealand meeting in Melbourne. They discuss the various environmental, physical and psychological triggers for heart disease.

Editor-in-Chief Dr Catherine Otto talks to Dr Carolyn Lam at the Cardiac Society of Australia & New Zealand meeting in Melbourne. They discuss her session on heart failure with preserved ejection fraction.

Editor-in-Chief Dr Catherine Otto talks to Dr David Calemajer at the Cardiac Society of Australia & New Zealand meeting in Melbourne. They discuss his session on managing the large spectrum of Ebstein's anomaly in adults in the absence of RCT data.

Alistair Lindsey talks to Martin Hülsmann and Noemi Pavo, both from the Medical University of Vienna, about their paper examining cardiovascular biomarkers in cancer patients. Paper: http://heart.bmj.com/content/early/2015/09/08/heartjnl-2015-307848.abstract

Chocolate is an important dietary source of flavonoid antioxidants, which are hypothesised to have a beneficial effect on endothelial function and protect against cardiovascular disease (CVD). In this podcast Dr Alistair Lindsay talks to Dr Phyo K Myint about his team's research into this topic. In order to evaluate any association between habitual chocolate consumption and the risk of cardiovascular events, they analysed data from the European Prospective Investigation into Cancer-Norfolk (EPIC-Norfolk), and incorporated the results from this observational study into the evidence available to date.

Aortic valve stenosis (AS) is a progressive disease, but the impact of baseline AS haemodynamic or anatomic severity on AS progression remains unclear. In this podcast Dr Alistair Lindsay talks to Dr Virginia Nguyen about her study to evaluate the impact of baseline AS severity assessed, either by using echocardiography (haemodynamic assessment) or MSCT (anatomic assessment) on AS progression.

Percutaneous Coronary Intervention (PCI) has a considerable evidence base and it is firmly established as the most common procedure used in the invasive treatment of patients with CHD in the UK. The evidence base relating to PCI has been reviewed and this has been published in Heart. The guidelines focus on issues pertinent to practice within the UK and set out a recommended template to ensure optimal delivery of patient care. Dr Alistair Lindsay speaks to Professor Adrian Banning from the John Radcliffe Hospital at the University of Oxford who was co-author on the guidelines.

Dr Alistair Lindsay speaks to Dr Tomasz Baron about his research which aimed to assess differences in incidence, clinical features, current treatment strategies and outcome in patients with type 2 vs. type 1 acute myocardial infarction (AMI). Full paper found here >> http://heart.bmj.com/content/101/2/101.full?sid=e9538ca9-604b-40af-95a7-c03f016f4c2e

Frailty in older age is known to be associated with cardiovascular disease (CVD) risk. However, the extent to which frailty is associated with the CVD risk profile has been little studied. Dr Alistair Lindsay talked to Dr Sheena Ramsay about her study and the clinical implications of the results. The original paper can be found here: http://heart.bmj.com/content/101/8/616.full?sid=767613b9-71bb-41af-80e8-361647c03828

Dr Alistair Lindsay speaks to Dr Edward Carlton about his published paper investigating whether a novel accelerated diagnostic protocol (ADP) for suspected acute coronary syndrome (ACS) could successfully identify low-risk patients suitable for discharge after a single high-sensitivity troponin T.

Dr Alistair Lindsay spoke to Dr Eliseo Guallar about his study to nvestigate the association between regular coffee consumption and the prevalence of coronary artery calcium (CAC) in a large sample of young and middle-aged asymptomatic men and women. Read the article here http://heart.bmj.com/content/early/2015/02/06/heartjnl-2014-306663.full?sid=3959ea9e-52ba-4e69-97fa-1b55aa2b9738

Alistair Lindsay talks to Scott Montgomery, honorary professor of epidemiology and public health, Institute of Epidemiology & Health, UCL, about his paper investigating physical fitness and stress resilience in adolescence and risk of coronary heart disease in middle age. Read the paper: http://heart.bmj.com/content/early/2015/02/10/heartjnl-2014-306703