Cvr Podcast Contagious Thinking

It is almost one year since the first positive case of COVID-19 confirmed in Scotland, and in this episode we talked with Clinical Research Fellow James Shepherd about how COVID-19 was introduced in Scotland from mainland Europe (https://www.nature.com/articles/s41564-020-00838-z). This work was a national effort involving multiple NHS and academic partners and demonstrates how pathogen genomic sequencing can support and enhance epidemiology and has the potential to inform public health intervention policy. You can find our previous content on at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Dr James Shepherd and Dr Elihu Aranday-Cortes. Editing: Elihu Aranday-Cortes. Music: Something Elated - Broke for Free freemusicarchive.org/music/Broke_For_Free

On the eve of the COVID-19 pandemic (Feb 2020), we welcomed a very special guest to Contagious Thinking, Associate Professor Dr Nuno Faria from the University of Oxford. In this episode, Nuno speaks with Vandana Ravindran and Elihu Aranday-Cortes, about his life in science and his interests in epidemiology and evolution of viruses circulating in human, vector and animal populations.

In this special episode for our Spanish speaking listeners, Mila and Elihu are talking with Professor Pablo Murcia about how viruses can infect different species, his scientific career and future work. Pablo -who is a DVM- is trying to understand the molecular and evolutionary mechanisms that underpin viral host switching and viral emergence.

In this episode, recorded in October 2019, we speak to Dr Jonathan Stoye - a Senior Group Leader at the Francis Crick Institute and Fellow of the Royal Society. In this episode we talk about Jonathan’s impressive research career path, from his first interest in the genetic interactions between retroviruses and their hosts. Jonathan also shares stories of how he made his way to his current role as a Senior Group Leader, including a memory of the late Professor Jim Neil. Featuring: Dr Jonathan Stoye and Dr Elena Sugrue Editing: Elena Sugrue Music: Ketsa-06-Day_Trips

Prof Nic Stonehouse from the University of Leeds talks to us about her career and how the right mentorship led her to a professorship studying picornaviruses. She also tells us about the exciting projects currently being developed in her lab looking at the replication of foot-and-mouth disease virus and the develop of empty viral capsids as potential vaccine candidates for poliovirus and enterovirus 71. Research in the Stonehouse group spans virology and RNA biology, applying novel approaches to the study of virus replication and assembly in three main research areas: 1) Picornaviral replication, 2) Design of novel virus-like particle vaccine; and 3)delivery of RNA aptamers into the skin as potential novel therapeutics. You can find our previous content on influenza over at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Prof Nicola Stonehouse, Dr Rute Pinto and Dr Patawee Asamaphan Editing: Rute Pinto Music: Day Trips by Ketsa

Dr. Andreas Wack from the Crick institute talks to us about the role of host immunity in the response to influenza virus and why we mount differential immune responses to infection. He also tells us why all forms of research are important in this age of emerging infections and we can never be too prepared!

Podcast S4 ep Dr Anna Cliffe from the University of Virgina (USA) talks about her career in science and research on herpes simplex latency and reactivation in neurons. You can find our previous content on at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Dr Anna Cliffe, Dr Vandana Ravindran and Dr Mila Collados Editing: Dr Mila Collados Music: Ketsa-06-Day_Trips

How do viral outbreaks arise? Can genomic epidemiology identify pathways of emergence of infectious diseases? In this episode of The Review we will answer these questions with Dr Kyriaki Nomikou, a Senior Research Fellow at the Centre for Virus Research who gives us a snapshot of the results and implications of her recent publication (https://doi.org/10.1371/journal.pbio.3000673 ) and the outcome of several years of collaboration between European scientists. You can find our previous content on at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Dr Kyriaki Nomikou and Dr Rute Maria Pinto. Editing: Rute Maria Pinto. Music: Something Elated - Broke for Free freemusicarchive.org/music/Broke_For_Free

Can viruses steal our genetic signals to generate human-virus genes? Can these proteins alter the course of viral infection? In this episode of the review recorded via zoom we will answer these questions with Dr Léa Meyer a Postdoctoral Researcher at the Centre for Virus Research who gives us a snapshot of the results and implications of her recent publication (https://doi.org/10.1016/j.cell.2020.05.035) and a wonderful story about scientists being nice to each other. You can find our previous content on at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Dr Léa Meyer and Dr Elena Sugrue. Editing: Elena Sugrue. Music: Something Elated - Broke for Free freemusicarchive.org/music/Broke_For_Free

Do bats deserve their bad rap when it comes to virus transmission? Do human viruses disproportionately originate from certain animal groups? In the this episode of 'The Review' we answer these questions with Nardus Mollentze, a research associate at the Centre for Virus Research who gives us a snapshot of the results and implications of his recent publication. (https://www.pnas.org/content/117/17/9423) You can find our previous content on at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Dr Nardus Mollentze and Dr Elena Sugrue. Edited and Produced by Elihu Aranday-Cortes. Music: Something Elated - Broke for Free freemusicarchive.org/music/Broke_For_Free

Today in a very special ad hoc episode, we have the personal experience from the inside of the coronavirus outbreak. From mainland China in Wuhan city, fellow postdoc Elihu Araday and Rute Pinto talked with Siyuan Hu, a PhD student in the Profesor Margaret Hosie's group, who is currently in Wuhan and living this outbreak from a different perspective. Featuring: Dr Elihu Araday-Cortes and Dr Rute Pinto and Siyuan Hu Editing: Elihu Araday-Cortes Music: Scott Holmes - Hopeful Journey https://freemusicarchive.org/music/Scott_Holmes

In this episode we’re extremely lucky to be welcoming Professor Diane Griffin, from the Johns Hopkins Bloomberg school of public health who is also the vice-president of the US National Academy of Sciences (http://www.nasonline.org/member-directory/members/3007695.html). Diane - who is an MD/PhD - is a pioneering expert in how viruses cause disease, focusing on those viruses that infect your brain (like measles), and viruses spread by insects (like alphaviruses, such as Sindbis and chikunungya viruses). In this episode, CVR PhD student Arthur Wickenhagen and ex-CVR postdoc Connor Bamford, chat with Diane about her inspiring career in virology, why she’s so fascinated with the brain and insect viruses, and the worrying rise in measles across the world. As always, you can find our previous content on measles and arboviruses over at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog Featuring: Prof Diane Griffin, Dr Connor Bamford and Mr Arthur Wickenhagen Editing: C

Can getting the flu reduce your chances of getting a cold? Can you get a cold and the flu at the same time? In the first episode of 'The Review' we answer these questions with Dr Sema Nickbakhsh, a research associate at the Centre for Virus Research who gives us a snapshot of the results and implications of her recent publication (https://www.pnas.org/content/116/52/27142) You can find our previous content on at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Dr Sema Nickbakhsh, Dr Elena Sugrue. Editing: Elena Music: Something Elated - Broke for Free freemusicarchive.org/music/Broke_For_Free

In this episode, Jack Hirst and Andrew Burns (on his podcast debut) are joined by Contagious Thinking veteran and founder Connor Bamford, who is crossing to other side and telling us about his own research on a peculiar immune protein that seems to make Hepatitis C infections worse rather than better. You can find our previous content on at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Connor Bamford, Jack Hirst and Andrew Burns Editing: Jack Hirst Music: Siesta - Jahzzar - freemusicarchive.org/music/Jahzzar

Season 3 Episode 10: In this episode of Contagious Thinking Connor and Elihu are talking with Dr Laura McCoy about why study and continue to study broadly neutralizing antibodies against HIV, and the role of B cell biology in HIV infection and vaccine responses. She also discusses her career so far, and gives advice to PhD and early career researchers. You can find our previous content on at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Dr Laura McCoy, Dr Connor Bamford and Dr Elihu Aranday-Cortes Editing: Elihu Aranday-Cortes Music: Siesta - Jahzzar - freemusicarchive.org/music/Jahzzar Photograph: Elihu Aranday-Cortes

Season 3 Episode 9: In this episode of Contagious Thinking Jack and Elena are talking with Dr Rachel Edgar about about her research investigating how the circadian clock of a host can affect viral infection, and how viruses can exploit our body clocks to aid their replication and spread. She also discusses her career so far, and gives advice to PhD and early career researchers. You can find our previous content on at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Dr Rachel Edgar, Jack Hirst and Dr Elena Sugrue Editing: Elena Sugrue Music: Siesta - Jahzzar - freemusicarchive.org/music/Jahzzar Photograph: Elihu Aranday-Cortes

Today on the Contagious Thinking podcast, Douglas and Elena are joined by Professor Rune Hartmann from Aarhus University who tells us about his work on understanding type III interferons, their role in immunity and viral infection and their evolution. He also describes some of his work with fruit flies and has some great advice for young scientists. You can find our previous content on influenza and cell biology over at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Prof. Rune Hartmann, Douglas Stewart and Dr Elena Sugrue Editing: Douglas Stewart Music: Siesta - Jahzzar - freemusicarchive.org/music/Jahzzar Photograph: Elihu Aranday-Cortes

In this episode, ex-postdoc Dr Connor Bamford will be speaking with Dr Rachel Ulferts from the Francis Crick Institute in London after she came to Glasgow recently to present her fascinating work. Dr Ulferts is currently a postdoc in the lab of Dr Rupert Beale at the Crick where she works on influenza virus and a cell process known as autophagy - or 'self eating'. Previously Rachel worked on a number of RNA viruses, like coronaviruses or picornaviruses in labs across Europe, including Northern Ireland and The Netherlands, before coming back to the UK to work at The University of Cambridge and then onto London. In this episode Connor talks with Rachel about her work on autophagy, her interest in fundamental virology, and her exciting plans for the future. You can find our previous content on influenza and cell biology over at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Dr Rachel Ulferts and Dr Connor Bamford. Editing: Dr Connor Bamford Music: Si

HUSH-ing HIV - A Podcast with Professor Paul Lehner Season 3 Episode 6: In this episode of Contagious Thinking Jack and Arthur are talking with Professor Paul Lehner about HIV and silencing of these viruses by the newly discovered HUSH complex. Paul talks about his career so far and his research on HIV. He further explains how he and colleagues discovered the HUSH complex and its role in silencing viruses like HIV. You can find our previous content on HIV over at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Prof Paul Lehner, Jack Hirst and Arthur Wickenhagen Editing: Arthur Wickenhagen Music: Siesta - Jahzzar - freemusicarchive.org/music/Jahzzar

In this special episode for our Spanish speakers listeners, Mila and Elihu are talking with Carolina Lopez about how viruses interact with the immune system during infection. As viruses copy their genomes, a large number of defective copies are made. Carolina studies the different forms of a virus, including those with regular and defective copies of their genome, that are present in an infection and how these different forms interact with the infected cell and influence its function. You can listen to all our podcasts at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. You can find our previous content on influenza over at cvrblog.myportfolio.com, email us at cvrcontagiousthinking@gmail.com or tweet us @CVRblog. Featuring: Carolina Lopez, Milagros Collados and Elihu Aranday Editing: Milagros Collados Music: Siesta - Jahzzar - freemusicarchive.org/music/Jahzzar